After you've installed Windows Updates for a while, you will find that there is a huge assortment of uninstall files in your C:\Windows folder that can be safely removed. Chances are, you aren't going to uninstall a hotfix unless it causes an issue. If you go to the C:\Windows directory, you will see folders starting with $NtUninstallKB (typically blue, which means compressed, if you have that folder option selected). Look at the "Date Modified" in "Details" view (View > Details) and remove any folders that aren't recent. If it's been years and you've never cleaned these up, there could be more than 100.